Thursday, March 28, 2013

Large robotic jellyfish could one day patrol oceans

Mar. 28, 2013 ? Virginia Tech College of Engineering researchers have unveiled a life-like, autonomous robotic jellyfish the size and weight of a grown man, 5 foot 7 inches in length and weighing 170 pounds.

The prototype robot, nicknamed Cyro, is a larger model of a robotic jellyfish the same team -- headed by Shashank Priya of Blacksburg, Va., and professor of mechanical engineering at Virginia Tech -- unveiled in 2012. The earlier robot, dubbed RoboJelly, is roughly the size of a man's hand, and typical of jellyfish found along beaches.

"A larger vehicle will allow for more payload, longer duration and longer range of operation," said Alex Villanueva of St-Jacques, New-Brunswick, Canada, and a doctoral student in mechanical engineering working under Priya. "Biological and engineering results show that larger vehicles have a lower cost of transport, which is a metric used to determine how much energy is spent for traveling."

Both robots are part of a multi-university, nationwide $5 million project funded by U.S. Naval Undersea Warfare Center and the Office of Naval Research. The goal is to place self-powering, autonomous machines in waters for the purposes of surveillance and monitoring the environment, in addition to other uses such as studying aquatic life, mapping ocean floors, and monitoring ocean currents.

Jellyfish are attractive candidates to mimic because of their ability to consume little energy owing to a lower metabolic rate than other marine species. Additionally, they appear in wide variety of sizes, shapes and colors, allowing for several designs. They also inhabit every major oceanic area of the world and are capable of withstanding a wide range of temperatures in both fresh and salt waters. Most species are found in shallow coastal waters, but some have been found in depths 7,000 meters below sea level.

Partner universities in the project are Providence College in Rhode Island, the University of California Los Angeles, the University of Texas at Dallas, and Stanford University. Priya's team is building the jellyfish body models, integrating fluid mechanics and developing control systems.

Cyro is modeled and named after the jellyfish cyanea capillata, Latin for Llion's Manemain jellyfishJellyfish, with "Cyro" derived from "cyanea" and "robot." As with its predecessor, this robot is in the prototype stage, years away from use in waters. A new prototype model already is under construction at Virginia Tech's Durham Hall, where Priya's Center for Energy Harvesting Materials and Systems is based.

"We hope to improve on this robot and reduce power consumption and improve swimming performance as well as better mimic the morphology of the natural jellyfish," Villanueva said, adding that the project also allows researchers such as himself to better understand aquatic creatures live. "Our hopes for Cyro's future is that it will help understand how the propulsion mechanism of such animal scales with size."

A stark difference exists between the larger and smaller robots. Cyro is powered by a rechargeable nickel metal hydride battery, whereas the smaller models were tethered, Priya said. Experiments have also been conducted on powering jellyfish with hydrogen but there is still much research to be done in that area.

In both cases, the jellyfish must operate on their own for months or longer at a time as engineers likely won't be able to capture and repair the robots, or replace power sources. "Cyro showed its ability to swim autonomously while maintaining a similar physical appearance and kinematics as the natural species," Priya said, adding that the robot is simultaneously able to collect, store, analyze, and communicate sensory data. This autonomous operation in shallow water conditions is already a big step towards demonstrating the use of these creatures."

How does the robot swim? Its body consists of a rigid support structure with direct current electric motors which control the mechanical arms that are used in conjunction with an artificial mesoglea, or jelly-based pulp of the fish's body, creating hydrodynamic movement.

With no central nervous system, jellyfish instead use a diffused nerve net to control movement and can complete complex functions. A parallel study on a bio-inspired control system is in progress which will eventually replace the current simplified controller. As with the smaller models, Cyro's skin is composed of a thick layer of silicone, squishy in one's hand. It mimics the sleek jellyfish skin and is placed over a bowl-shaped device containing the electronic guts of the robot. When moving, the skin floats and moves with the robot, looking weirdly alive.

"It has been a great experience to finally realize the biomimetic and bio-inspired robotic vehicles," Priya said. "Nature has too many secrets and we were able to find some of them but many still remain. We hope to find a mechanism to continue on this journey and resolve the remaining puzzles."

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The above story is reprinted from materials provided by Virginia Tech (Virginia Polytechnic Institute and State University), via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/kLqBg1DBw1g/130328124807.htm

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Obama must support global Arms Trade Treaty

The global arms trade is out of control. In armed conflicts from Syria to Sudan, Mali to Myanmar, and Congo to Columbia, thousands of people are slaughtered by weapons of war that are transferred by governments into the hands of unscrupulous regimes, criminals, illegal militias, and terrorist groups.

The unregulated global arms trade, which increases the availability of small arms and ammunition in conflict zones, is fueling wars and human rights abuses against civilians. More than 740,000 men, women and children die each year as a result of armed violence.

The deaths caused each year are at the center of a larger tragedy. The poorly regulated arms trade makes development in war-torn countries more difficult. For example, the prevalence of AK-47?s and ammunition in the rural areas of South Sudan, a country plagued by five decades of war, is having devastating effects on peace-building and poverty-eradication efforts.

OPINION: 5 ways US must promote nuclear nonproliferation

The time for action to reduce the illicit, unregulated flow of weapons and ammunition is now.

Rather than watching this destruction from afar, the international community has an opportunity to offer a solution. Diplomats from the United States and more than 150 other countries are at the United Nations in New York for the ?final? round of negotiations (set to conclude tomorrow) for a legally binding Arms Trade Treaty. The treaty would restrict the flow of weapons across borders and close the loopholes unscrupulous traders now navigate with impunity.

Last July, the US was among a handful of states that failed to join a consensus on the treaty during the last hour of negotiations, saying "more time was needed" to complete the process. Now, the Obama administration has had that time.

President Obama and Secretary of State John Kerry must now work with other countries at the United Nations to close the deal on a robust, effective Arms Trade Treaty with the highest possible standards. The Arms Trade Treaty will not, by itself, prevent all illicit and irresponsible arms trafficking, but it will help reduce the enormous toll of armed conflict around the globe.

Mr. Obama should join other leaders to finalize a treaty that outlaws arms deals where the exporter knows or should know that the weapons will be used to commit the world?s worst crimes. No country should be able to hide behind ambiguous international law to aid and abet genocide, crimes against humanity, serious war crimes, or a consistent pattern of serious human rights abuses.

The treaty should also require each country to assess the risks associated with an arms deal prior to transfer and be required to not transfer the weapons if there is a substantial risk that the arms will be used to commit or facilitate serious violations of international human rights, the laws of war, or acts of terrorism.

The implementation of an Arms Trade Treaty based on this standard would prevent, or at least make it more difficult to justify, the ongoing supply of weapons to the Assad regime in Syria, for example.

While the US has some of the strictest regulations governing the export and import of weapons, less than half of the countries in the world have any basic laws governing arms trade. That?s why the treaty must mandate that countries adopt and enforce comprehensive legal regime to regulate the import and export of all conventional weapons and ammunition. Arms dealers have no problem finding countries to base their operations and escape law enforcement. The treaty must close this lethal loophole.

The treaty must also avoid other loopholes ? like the one sought by India and opposed by the US ? that would exempt arms deals made under previous defense cooperation agreements from the treaty. And finally, the treaty should ensure that states make their reports on arms transfers available to the public to improve accountability.

THE MONITOR'S VIEW: For Obama's second term, a call to arms control

The Arms Trade Treaty is about making it harder for irresponsible states and arms dealers to put profits ahead of people. It is a vital tool to help protect civilians, aid workers, and missionaries from the violence fueled by the illicit arms trade. Its time is now.

Daryl G. Kimball is the executive director of the Arms Control Association.

Raymond C. Offenheiser is president of Oxfam America.

ALSO BY DARYL KIMBALL: Time to curb the illicit global arms trade

ALSO BY RAYMOND OFFENHEISER: How to make US foreign aid work

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Source: http://news.yahoo.com/obama-must-support-global-arms-trade-treaty-140817424--politics.html

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Wednesday, March 13, 2013

'Clone Wars' Canceled: What's Next For 'Star Wars' On TV?

A day after the sad, sad news that Lucasfilm had decided to cancel "Star Wars: The Clone Wars," fans of the series are left with lots and lots of questions about what's going on and what it means for the future of "Star Wars" on TV. After thinking over the news for a day, we [...]

Source: http://moviesblog.mtv.com/2013/03/13/clone-wars-canceled-star-wars-on-tv/

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ESRB Issues Changes for Marketing of Mature Games ? GamingBolt ...

esrb mature rating
The ESRB has issues a new bevy of changes for the marketing of games rated ?M? for Mature. Some of these allow for more open marketing of an M-rated game, including cutting trailers or videos for general audiences and no longer requiring an age-gate when viewing said videos online.

Of course, these same trailers must be sent to the ESRB for pre-approval. Also, when cross selling products aka bundling an exclusive demo for a game with another, an M-rated game may be bundled with a lesser-rated game but only after explicit approval from the ESRB. This is to insure that games being cross-sold ?have the same intended audience?.

Finally, with Mature demos, a four second warning regarding the game?s content matter is no longer needed. Instead, the rating must be prominently featured on the demo?s download page. Also, ratings from other organizations cannot be displayed side-by-side with ESRB ratings (this includes Europe?s PEGI system).

Thoughts on the changes?

Source: GiantBomb

Source: http://gamingbolt.com/esrb-issues-changes-for-marketing-of-mature-games

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Single-Family ? 325 Singletary Ln Framingham, MA 01702 is now ...

This wonderful Woodcrest Acres Colonial has been lovingly cared for, maintained and updated. Not your average floor plan this 4 bedroom 2 full bath home offers charm and character. Kitchen is updated with stainless appliances and granite counters and has a sun filled eat in area. Large fireplaced living room open to Dining Room is great for entertaining. Finished fireplaced basement is a great play room area and the screened porch overlooks a lovely yard for dining al fresco! Don?t wait on this!

This is a Colonial style home and features 7 total rooms, 2 full baths, 4 bedrooms, 0.52 Acres, and is currently available for $425,000.

For complete details click here.

Source: http://www.metrowesthomesandlife.com/2013/03/single-family-325-singletary-ln-framingham-ma-01702-is-now-new-to-the-market/

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Tuesday, March 12, 2013

Will Smith Still Has It, Sings 'Fresh Prince' Theme

Will Smith surprised a bunch of students in England with an impromptu performance of the song that made him a star. He's still got it. Also, find out what "Monsters University" has to offer you in today's Dailies! » Every suit Robert De Niro wore in "Casino" [reddit] » John Malkovich will play Blackbeard in [...]

Source: http://moviesblog.mtv.com/2013/03/11/will-smith-fresh-prince/

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Monday, March 11, 2013

The day Johnny Carson asked if anyone in the audience played piano (Americablog)

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Therapies for ALL and AML targeting MER receptor hold promise of more effect with less side-effect

Therapies for ALL and AML targeting MER receptor hold promise of more effect with less side-effect

Monday, March 11, 2013

Two University of Colorado Cancer Center studies show that the protein receptor Mer is overexpressed in many leukemias, and that inhibition of this Mer receptor results in the death of leukemia cells ? without affecting surrounding, healthy cells.

The first study, published today in the journal Oncogene, worked with acute myeloid leukemia (AML), for which current chemotherapies offer a cure rate of only about 55 percent.

"In about 2/3 of all AML patients and about 90 percent of adult AML patients, we found that the Mer receptor was upregulated. Mer receptor protein shouldn't exist in normal myeloid cells, but we found it abnormally expressed," says Doug Graham, MD, PhD, investigator at the CU Cancer Center and associate professor of pediatrics and immunology at the University of Colorado School of Medicine.

The Mer receptor sits within the cell membrane, and when it becomes activated the cell receives signals to grow and survive. Leukemia and perhaps many solid cancers have taken advantage of Mer's cell survival function to assist the cancer's rampant proliferation. When Graham and colleagues used shRNA to silence the production of Mer in leukemia cells, they showed decreased leukemia cell survival, increased sensitivity to existing chemotherapies and longer survival in mouse models of leukemia.

A second study, published this month in Blood Cancer Journal, shows similar results with acute lymphoblastic leukemia (ALL), the most common pediatric cancer.

"The ALL cure rate is already over 80 percent, but for patients who relapse, the prognosis is much less optimistic. We need targeted therapies to use as second-line treatments for the population for whom existing therapies aren't lasting, particularly in patients with relapsed T cell ALL," Graham says.

Second, he points out that a quarter of pediatric ALL patients who respond to existing chemotherapies do so at the price of significant long-term side-effects. "And so in addition to increased survival, the second goal of targeted therapies is decreased side-effects," Graham says.

Inhibition of the Mer protein receptor is promising on both accounts.

"Not only do B-cell and T-cell leukemia cells die when you knock down Mer receptor expression, but these cells are also much more sensitive to existing chemotherapies. By hitting Mer, we're making the chemotherapy more effective," Graham says.

In ALL and AML, Graham's studies show that making Mer inhibition means that less chemotherapy may have equal or stronger effect. Strong preliminary evidence shows that Mer may be the key to less toxic, more effective therapies for leukemia.

###

University of Colorado Denver: http://www.ucdenver.edu

Thanks to University of Colorado Denver for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127232/Therapies_for_ALL_and_AML_targeting_MER_receptor_hold_promise_of_more_effect_with_less_side_effect

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Security threats, fractures plague US and Afghans

U.S. Secretary of Defense Chuck Hagel, left, meets with Afghanistan's Interior Minister Ghulam Mujtaba Patang at the ISAF (International Security Assistance Force) headquarters in Kabul, Sunday, March 10, 2013. It is Hagel's first official trip since being sworn-in as Obama's Defense Secretary. (AP Photo/Jason Reed, Pool)

U.S. Secretary of Defense Chuck Hagel, left, meets with Afghanistan's Interior Minister Ghulam Mujtaba Patang at the ISAF (International Security Assistance Force) headquarters in Kabul, Sunday, March 10, 2013. It is Hagel's first official trip since being sworn-in as Obama's Defense Secretary. (AP Photo/Jason Reed, Pool)

U.S. Secretary of Defense Chuck Hagel, second left, walks with Afghan Brig. Gen. Aminullah Patyani, left, commander of the Kabul Military Training Center, upon his arrival at the facility in Kabul, Afghanistan, Sunday, March 10, 2013. Hagel is on his first trip to Afghanistan as defense secretary. (AP Photo/Jason Reed, Pool)

U.S. Secretary of Defense Chuck Hagel, center, talks with members of the U.S. Army and Marines during his visit to the Kabul Military Training Center in Kabul, Afghanistan, Sunday, March 10, 2013. Hagel is on his first trip to Afghanistan as defense secretary. (AP Photo/Jason Reed, Pool)

U.S. Secretary of Defense Chuck Hagel, left, is greeted by members of the U.S. Army and Marines during his visit to the Kabul Military Training Center in Kabul, Afghanistan, Sunday, March 10, 2013. Hagel is on his first trip to Afghanistan as defense secretary. (AP Photo/Jason Reed, Pool)

U.S. Secretary of Defense Chuck Hagel, center left, shakes hands with a female Afghan non-commissioned officer under training, during his visit to the Kabul Military Training Center in Kabul, Afghanistan, Sunday, March 10, 2013. Hagel is on his first trip to Afghanistan as defense secretary. (AP Photo/Jason Reed, Pool)

(AP) ? A series of security problems and difficult fractures in relations with Afghan leaders plagued Defense Secretary Chuck Hagel's first trip here as Pentagon chief, including the Afghan president's accusations that the U.S. and the Taliban are working in concert to show that violence in the country will worsen if most coalition troops leave.

The top U.S. commander in Afghanistan, Gen. Joseph Dunford, quickly rejected the charges President Hamid Karzai made Sunday as "categorically false." But the accusations were just the latest in a series of disputes that have frayed relations between the two nations as the U.S. works to wind down the war and turn the country's security over to the Afghans.

Speaking to reporters shortly after Karzai made the comments, Dunford said the Afghan leader has never expressed such views to him but said it was understandable that tensions would arise as the coalition balances the need to complete its mission with the Afghans' move to exercise more sovereignty.

"We have fought too hard over the past 12 years, we have shed too much blood over the past 12 years, we have done too much to help the Afghan security forces grow over the last 12 years to ever think that violence or instability would be to our advantage," said Dunford.

Dunford's comments came, however, soon after U.S. officials cancelled a news conference with Hagel and Karzai because of a security threat ? just a day after a suicide bomber on a bicycle struck outside the Afghan Defense Ministry, killing nine Afghan civilians and wounding 14 others. Hagel heard the explosion from the safe location where he was meeting with Afghan officials but was never in danger.

The security problems compounded a series of flare-ups in recent weeks, including a dispute that has stalled the transfer of a U.S. prison to Afghan authority as well as Karzai's order to expel U.S. special operations forces out of Wardak province, which lies just outside the capital, because of allegations that Afghans working with the commandos were involved in abusive behavior.

Hagel and Karzai still planned to meet privately Sunday, and some of the ongoing issues were likely to come up. The U.S. and Afghan leaders are in the midst of negotiations over the long-term presence of American forces in Afghanistan beyond the end of 2014, when all combat troops are scheduled to leave.

U.S. officials would not provide details on the security concerns that led to cancelling the news conference. They spoke on condition of anonymity because they weren't authorized to discuss the matter publicly. But Pentagon press secretary George Little said the cancellation was not due to Karzai's earlier comments about the U.S. and the Taliban.

During a nationally televised speech, Karzai said two suicide bombings that killed 19 people on Saturday ? the one outside the Afghan Defense Ministry and the other near a police checkpoint in eastern Khost province ? show the insurgent group is conducting attacks to help show that international forces will still be needed to keep the peace after their current combat mission ends in 2014.

"The explosions in Kabul and Khost yesterday showed that they are at the service of America and at the service of this phrase: 2014. They are trying to frighten us into thinking that if the foreigners are not in Afghanistan, we would be facing these sorts of incidents," he said during the speech about the state of Afghan women.

Karzai is known for making incendiary comments in his public speeches. And Dunford on Sunday said that some of the recent disputes between the U.S.-led coalition and Afghan leaders "strike at the heart of sovereignty" and could be more political in nature. He said Karzai may be doing what he needs to do to communicate with the Afghan people and their political leaders outside the government.

Dunford also rejected the suggestion that the recent friction reflects an erosion in the U.S. relationship with Afghanistan.

"We do not have a broken relationship, we do not have a lack of trust," said Dunford, adding that none of the political dust-ups have bled over into his dealings with his Afghan security force counterparts. He said efforts to train and advise the Afghan security forces have continued and that plans for them to be in the lead for security across the country later this summer are on track.

Dunford would not detail why the scheduled transfer of the Parwan Detention Center was delayed again and called it a difference in perspective. But he made clear that the U.S. believes it must retain the power to insure that detainees who are deemed to be security threats remain in custody.

Currently, there is an Afghan administrator of the prison, which is located about an hour outside the capital, but the Americans have veto power over the release of detainees. The prisoners held under American authority do not have the right to a trial because the U.S. considers them detainees held as part of an ongoing conflict.

Regarding the move to expel the special operations forces, Dunford said he spoke to Karzai about the issue on Saturday and told him the U.S. is working on a plan to transition security in the Wardak region to Afghan forces. He would not directly say whether the commandos will stay in Wardak when the deadline to leave comes on Monday. But he said Karzai knows they are working on the plan and has not yet issued a directive to the force.

___

Associated Press writers Heidi Vogt and Rahim Faiez contributed to this report.

___

Follow Lolita C. Baldor on Twitter: http://twitter.com/lbaldor

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-03-10-AS-US-Afghanistan/id-1e61a22ee38944578525c16177b57734

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Security threat cancels Hagel, Karzai press event

KABUL, Afghanistan (AP) ? U.S. officials say a news conference with Defense Secretary Chuck Hagel and Afghan President Hamid Karzai is cancelled because of a security threat, but the two men plan to meet privately.

The cancellation comes a day after a suicide bomber on a bicycle struck outside the Afghan Defense Ministry killing nine Afghan civilians and wounding 14 others.

U.S. officials would not provide details on the security concerns. They spoke on condition of anonymity because they weren't authorized to discuss the matter publicly.

Pentagon press secretary George Little said the cancellation was not due to remarks Karzai made earlier suggesting that the Taliban and the U.S. are working in concert to convince Afghans that violence will worsen if most foreign troops leave as planned by the end of next year.

Source: http://news.yahoo.com/security-threat-cancels-hagel-karzai-press-event-131538530.html

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Blog Carnival - work life balance and goal setting - Mar 10, 2013 ...

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